Assessment of Fc-mediated Functional Activity for the Development of Complex Biologics and Bioconjugates, Upcoming Webinar Hosted by Xtalks

In this free webinar, learn the best approaches to assess Fc function (antibody-dependent cellular cytotoxicity [ADCC], antibody-dependent cellular phagocytosis [ADCP] and complement-dependent cytotoxicity [CDC]) for drug discovery and development programs. Attendees will gain insights into the benefits and challenges of complex assay formats like real-time spheroid cytotoxicity assays. The featured speakers will share how to design and develop successful Fc-mediated functional assays, including the selection of target cell lines, effector cells and appropriate controls.

TORONTO, Jan. 7, 2025 /PRNewswire-PRWeb/ -- In this webinar, the expert speakers will review strategies for phase-appropriate assessment of Fc-mediated functional activity and present new developments for complex modalities.

The success of many cancer therapeutics lies in their ability to induce cytotoxicity by NK cells (antibody-dependent cellular cytotoxicity (ADCC)), phagocytosis (antibody-dependent cellular phagocytosis (ADCP)) and complement-dependent cytotoxicity (CDC) against specific targets; therefore, appropriate assessment is crucial before progressing a drug into the clinic.

Importantly, demonstrating the lack of unwanted effector functions is required for safety purposes. During this webinar, the expert speakers will consider the key aspects for developing successful Fc-mediated functional assays and will review the benefits and challenges of a panel of assay formats for different purposes.

They will also present options for choosing the most suitable target cell lines, effector cells and appropriate controls. Moreover, they will showcase studies on how rigorous data trending leads to reliable assays and how more complex formats, such as how real-time spheroid cytotoxicity assays contribute to understanding the mode of action and selecting the most promising lead.

Register for this webinar to obtain an overview of how Fc-mediated functions (or lack of) are essential to the success of biologic drugs and how best to evaluate these functions.

Join experts from Abzena, Rosa Gonzalez-Serrano, Senior Manager; and Erika Kovacs, Senior Director, for the live webinar on Thursday, January 23, 2025, at 11:30am EST (4:30pm GMT).

For more information, or to register for this event, visit Assessment of Fc-mediated Functional Activity for the Development of Complex Biologics and Bioconjugates.

ABOUT XTALKS

Xtalks, powered by Honeycomb Worldwide Inc., is a leading provider of educational webinars and digital content to the global life science, food, healthcare and medical device communities. Every year, thousands of industry practitioners (from pharmaceutical, biotechnology, food, healthcare and medical device companies, private & academic research institutions, healthcare centers, etc.) turn to Xtalks for access to quality content. Xtalks helps professionals stay current with industry developments, regulations and jobs. Xtalks webinars also provide perspectives on key issues from top industry thought leaders and service providers.

To learn more about Xtalks visit https://xtalks.com

For information about hosting a webinar visit https://xtalks.com/why-host-a-webinar/

Media Contact

Vera Kovacevic, Xtalks, +1 (416) 977-6555 x371, vkovacevic@xtalks.com, https://xtalks.com/

View original content to download multimedia:https://www.prweb.com/releases/assessment-of-fc-mediated-functional-activity-for-the-development-of-complex-biologics-and-bioconjugates-upcoming-webinar-hosted-by-xtalks-302343115.html

SOURCE Xtalks